MIT Department of Electrical Engineering & Computer Science

E E C S

A FAB FACILITY FOR DNA SEQUENCING

Kevin Ulmer
seQ, Ltd.

Thursday, September 21, 1995
4:00 PM (3:30 refreshments)
Room 36-428 (RLE Conference Room)
BAMS Seminar

Abstract

The first complete DNA sequence of the genome of a free-living microorganism has recently been published (1995 Science 269:496). At only 1.8 million base pairs, it is dwarfed by the 3 billion base pair human genome which is the ultimate goal of the international Human Genome Project. The strategy for scaling up DNA sequencing to address this challenge is currently the subject of heated debate within the genome community. Is there a "Moore's Law" equivalent for DNA sequencing, and what lessons from the history of semiconductor manufacturing might productively be applied to the sequencing of genomes? This talk will explore the technological and economic parallels between these disparate fields, and examine the options for scale-up, the role of MEMS technology, and their implications for the future of large-scale DNA sequencing.


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Created: Sep 18, 1995  | Modified: Jun 25, 1997
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